Disclaimer

Hamppumaa -site strives to ensure that all information on this site is accurate and up to date. Nevertheless, the content may contain errors and omissions that the user of the site must take into account and confirm the information as necessary. No content presented on this site is presented as an allegation or accurate information. The images on the site are intended to provide an overview only, as the features and design of the products may change.

The webmaster is not in a position to control how the user of the site uses the content of the site and is therefore not liable for any direct, indirect, indirect, consequential, punitive or other damages that may result directly or indirectly from the use of the site’s data.

Nothing herein restricts consumer rights as defined by the Consumer Customers Act.

The user is always obliged to check the instructions for use of the products before use. If the product has a defect within the meaning of the Consumer Protection Act, you are entitled to a refund. You can request that the error be corrected or that the product be replaced with an error-free one.

Hamppumaa -site contains links and references to other websites. The webmaster of the site has not been able to check the entire content of all linked sites and is therefore not responsible for their content. The user of the site moves to other sites at his own risk and is responsible for the use of other sites in accordance with the terms of use.

CBD INTERACTIONS WITH MEDICINES

The combination of CBD and certain drugs may significantly increase or decrease the efficacy of the drug. If you are using products belonging to the group of medicines below, we recommend that you discuss the use of CBD-A products with your doctor.

CBD AND EPILEPSY

In clinical trials, CBD has been shown to reduce epileptic seizures, e.g. in patients with Dravet’s syndrome. However, concomitant use of CBD and antiepileptic drugs has caused side effects in some patients. They have been common with carbamazepine (Tegretol), among others.

Other medicines that may interact:
Absenor, Deprakine, Orfiril, Frisium, Inovelo, Topimax, Zonegran, Zebinix.

CBD AND CHEMOTHERAPY

Many chemotherapy drugs are metabolized by the cytochrome p450 enzyme and may therefore have strong interactions with CBD. Caution should be exercised when using CBD with at least the following drugs:

• Etoposide (e.g. Etoposide, Eposin)
• Methotrexate (Metoject)
• Paclitaxel (Paclitaxin, Paclitaxel)

Interactions are not always negative. For example, the combination of paclitaxel and CBD reduces the resulting neuropathic pain.

CBD AND CARDIOVASCULAR MEDICINAL PRODUCTS

CBD can interact with many heart medications, such as statins. Statins are drugs for fat metabolism that inhibit the liver’s own cholesterol synthesis. The liver thus produces less cholesterol-containing particles in the bloodstream. There are also several beta-blockers on the interaction list.

• Tikagrelori (Brilique)
• Quinidine (Kiniduron)
• Atorvastatin (Lipitor)
• Seliprolol (Selectol)
• Amiodarone (Cordarone)
• Clobidogrel
• Carvedilol
• Nifedipine (Adalat, Procardia)
• Valsartan (Valsartan, Diovan)
• Pitavastatin (Livazo, Vezepra)

CBD AND MENTAL MEDICINES

Most antidepressants do not interact with CBD. Buspirone (Aksilon, Buspiron), used to treat generalized anxiety disorder, is often prescribed in addition to antidepressants. It is metabolised by the cytochrome p450 enzyme and may therefore have strong interactions with CBD. Clomipramine (Anafranil) also has similar strong interactions.

CBD AND BLOOD PRESSURE MEDICINES (calcium channel blockers)

Calcium channel blockers, blood thinners, and medications used to treat high blood pressure and arrhythmias can cause severe symptoms with CBD. CBD reduces or prevents the breakdown of drugs, for example, with warfarin (Marevan), enhancing its effect.

OTHER drugs that cause interactions are at least listed below.

• Valsartan (Amlodipine, Valsartan)
• Verapamil
• Nifedipine (Adalat, Nifedipine Alternova)
• Diltiazem (Cardizem)
• Isradipine (Lomir)
• Torasemidi (Torasemid, Torem)
• Felodipine (Felodipine, Plendil)
• Amlodipine (Ampodipine)

CBD AND SOOTHING AGENTS (benzodiazepines)

Benzodiazepines are used to treat anxiety, insomnia, nausea, depression and panic disorder.

Some benzodiazepines, such as alprazolam (Alprox, Xanor, Alprazolam) and diazepam (Diapam, Diazepam Accord), do not degrade as rapidly as CBD. As a result, their concentrations may become too high.

• Alprazolam (Alprox, Xanor, Alprazolam, Xanax)
• Triazolam (Triazolam, Halcion)
• Diazepam (Diapam, Diazepam Accord)
• Midazolam (Dormicum, Midazolam)
• Quatsepam (Aldizem, Cardizem)
• Triazolam (Triazolam, Halcion)

CBD AND ANTIOBIOTS

In particular, fluoroquinolones (Ciprofloxacin) may interact strongly with CBD.

• Ciprofloxacin
• Gemifloxacin
• Levofloxacin
• Moxifloxacin
• Norfloxacin Sandoz
• Ofloxacin (Tarivid, Exocin)
• Rifampicin (Rimapen)

CBD AND OTHER INTERACTION MEDICINES

Cholesterol: lovastatin (Mevacor, Lovastatin)
Antimicrobials: ketoconazole (Nizoral) & itraconazole (Sporanox)
Cortisone preparation: methylprednisolone (Solu-Medrol, Solomet)
Antihistamines: fexofenadine (R Fexorin) & terfenadine (Telfast)
Erectile Dysfunction: sildenafil (Viagra)
Cholesterol lowering drug: simvastatin (Simvastatin, Zocor)
Barbiturate: Hexobarbital